A history of nitrous oxide and oxygen anaesthesia IVD: Henry Hill Hickman in his time.

A history of nitrous oxide and oxygen anaesthesia. IVC: Henry Hill Hickman in his time.

Previous verdicts on Hickman set the scene. The genealogy of Hickman and his wife is explored, disclosing the identities of "Poor Mrs Dudley of Shut End" and "Thomas Dudley of Kingswinford". Some previous evidence is explained by the bankruptcy of Hickman's father-in-law. The dubious means whereby Hickman qualified prematurely are examined.

A history of nitrous oxide and oxygen anaesthesia. Part V: The crucial experiment, its eclipse, and its revival.

The quest for Hickman.

Henry Hill Hickman (1800-1830), "the Rupert Brooke of anaesthesia",1 has a wellestablished place in medical history. A Shropshire general practitioner, who died young, he successfully carried out minor surgical procedures on animals rendered insensible by carbon dioxide and published his results in 1824 in a locally-printed pamphlet, which was reviewed unfavourably in the Lancet and Gentleman's...

The evolution of anaesthesia. 4. Pneumatic medicine.

ALTHOUGH none of the work done by the eighteenth-century scientists forms a direct link with anaesthesia, yet knowledge of any kind is bound to influence the future. The discovery of gases in the second half of the century was not only of profound consequence to chemistry, but also to medicine and the world. In order to understand how the discovery of anaesthesia is placed in history, it is nec...

Nitrous oxide-mediated activation of the EEG during isoflurane anaesthesia in patients.

We have studied the effects of nitrous oxide on EEG burst suppression patterns during stable isoflurane anaesthesia in 13 ASA I patients. After induction of anaesthesia with propofol, the concentration of isoflurane was increased with continuous EEG monitoring to burst suppression level (mean end-tidal concentration of isoflurane, 1.7 (SD 0.2)%), and kept constant during the study. During surge...